摘要
目的 了解2003-2022年江苏省苏州市膀胱癌死亡趋势和寿命损失情况,为完善膀胱癌防治策略提供参考.方法 通过苏州市居民死亡登记系统收集2003-2022年苏州市膀胱癌死亡病例资料,包括年龄、性别、死亡日期和根本死因等,计算粗死亡率、标化死亡率、潜在减寿年数(PYLL)、标化潜在减寿年数(SPYLL)、潜在减寿率(PYLLR)、标化潜在减寿率(SPYLLR)和平均减寿年数(AYLL),采用平均年度变化百分比(AAPC)分析膀胱癌死亡和寿命损失变化趋势.结果 2003-2022年苏州市膀胱癌死亡病例2 978例,粗死亡率为2.22/10万,呈上升趋势(AAPC=4.271％,P＜0.05);标化死亡率为0.91/10万,无明显变化趋势(P＞0.05).男性膀胱癌标化死亡率为1.58/10万,无明显变化趋势(P＞0.05);女性标化死亡率为0.37/10万,呈下降趋势(AAPC=-2.331％,P＜0.05).年龄别粗死亡率在＜45岁处于较低水平,45岁后上升,≥60岁达到最高.≥60岁男性膀胱癌粗死亡率呈上升趋势(AAPC=2.864％,P＜0.05),≥60岁女性无明显变化趋势(P＞0.05).苏州市膀胱癌PYLL为5 020.00人年,SPYLL为2 945.14人年,PYLLR为0.04‰,SPYLLR 为 0.03‰,AYLL 为 9.07 年/人;2003-2022 年 SPYLL、SPYLLR 和 AYLL 均呈下降趋势(AAPC=-2.867％、-3.321％和-3.738％,P＜0.05).结论 2003-2022年苏州市膀胱癌死亡率呈上升趋势,PYLL呈下降趋势,60岁及以上男性人群是膀胱癌防控的重点人群.
Abstract
Objective To analyze the trends in mortality and life lost due to bladder cancer in Suzhou City,Jiangsu Province from 2003 to 2022,so as to provide the reference for prevention and treatment strategy of bladder cancer.Methods The data of bladder cancer death in Suzhou City from 2003 to 2022 were collected through Suzhou Resi-dents1 Death Registration System,including age,gender,date of death and underlying cause of death.The crude mortali-ty,standardized mortality,years of potential life lost(PYLL),standardized years of potential life lost(SPYLL),years of potential life lost rate(PYLLR),standardized years of potential life lost rate(SPYLLR)and average years of life lost(AYLL)were calculated.The average annual percent change(AAPC)was used to analyze the trends in bladder can-cer death and life lost.Results Totally 2 978 deaths occurred due to bladder cancer in Suzhou City from 2003 to 2022.The crude mortality was 2.22/105,which appeared a tendency towards a rise(AAPC=4.271％,P＜0.05).The stan-dardized mortality was 0.91/105,which appeared no significant changing trend(P＞0.05).The standardized mortality was 1.58/105 in males and 0.37/105 in females,which appeared no significant tendency in males(P＞0.05)and appeared a tendency towards a decline in females(AAPC=-2.331％,P＜0.05).The age-specific crude mortality was low among peo-ple who aged under 45 years,began to rise among people aged over 45 years and peaked among people aged 60 years and older.The crude mortality of bladder cancer in males aged 60 years and older showed an increasing trend(AAPC=2.864％,P＜0.05),but there was no significant tendency in females aged 60 years and older(P＞0.05).The PYLL,SPYLL,PYLLR,SPYLLR and AYLL of bladder cancer were 5 020.00 person-years,2 945.14 person-years,0.04‰,0.03‰ and 9.07 years per person.SPYLL,SPYLLR and AYLL showed an decreasing trend(AAPC=-2.867％,-3.321％,-3.738％,P＜0.05).Conclusions The mortality of bladder cancer in Suzhou City appeared a tendency towards a rise from 2003 to 2022.The PYLL appeared a downward trend.Males aged 60 years and older are the key groups for the prevention and control of bladder cancer.
基金项目
江苏省老年健康科研项目(LKM2023038)
南京医科大学姑苏学院公共卫生专项重点项目(GSKY20230103)
南京医科大学姑苏学院科研项目(GSKY20210305)
万方数据