Objective To investigate the clinical and molecular epidemiological characteristics of 10 patients with entero-virus(EV)-D68 infections in the respiratory tract in Shaoxing City,Zhejiang Province,so as to provideinsights into for-mulation of control interventions for EV-D68 infections.Methods Clinicalspecimens were sampled from patients with acute respiratory tract infections(ARTIs)admitted to sentinel hospitals in Shaoxing City from 2021 to 2022,and EV-D68 was detected using real-time fluorescent PCR assay and sequencing of the VP1 region of enterovirus.The epidemi-ological and etiological characteristics of EV-D68 infected cases were descriptively analyzed.Results A total of 3 009 specimens were sampled from patients with ARTIs from 2021 to 2022,and the detection of EV-D68 was 0.33％.Of all EV-D68-infected patients,there were 6 men and 4 women,and 5 cases under 18 years of age,2 cases at ages of 18 to 60 years and 3 cases at ages of over 60 years.EV-D68 infection predominantly occurred in summer(5 cases detect-ed between May and July)and autumn(5 cases detected between September and October).The main clinical symptoms included fever(10 cases),sore throat(9 cases)and cough(8 cases),and all 10 cases recovered well,with no deaths re-ported.Sequencing identified D3 subtype in all 10 specimens positive for EV-D68.Conclusions The ARTIs caused by EV-D68 occurred predominantly among children under 18 years of age in Shaoxing City,and was highly prevalent in summer and autumn.D3 was the predominant enterovirus subtype.
维普
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