Objective To analyze the disease burden and risk factors of colorectal cancer in Zhejiang Province from 1990 to 2019,so as to provide the basis for prevention and control of colorectal cancer.Methods Based on data of 2019 Global Burden of Disease(GDB 2019),disease burden and risk factors of colorectal cancer in Zhejiang Province from 1990 to 2019 was assessed using years of life lost(YLL),years lived with disability(YLD),disability-adjusted life years(DALY).Results In 2019,the YLL rate,YLD rate and DALY rate caused by colorectal cancer in Zhejiang Prov-ince were 496.15/105,31.81/105 and 527.96/105,respectively.From 1990 to 2019,the YLL rate,YLD rate and DALY rate caused by colorectal cancer in Zhejiang Province increased by 114.90％,482.60％and 123.38％,respectively,show-ing increasing trends(average annual percent change values were =2.663,6.283 and 2.800,respectively,all P<0.05).From 1990 to 2019,the YLL rate,YLD rate and DALY rate in the age groups of 15 to 49 years,50 to 69 years and 70 years and older showed increasing trends(all P<0.05).In 1990,the top ten risk factors for colorectal cancer in Zhe-jiang Province were diet low in calcium,diet low in milk,diet low in whole grains,smoking,alcohol use,low physical activity,high fasting plasma glucose,diet high in red meat,diet low in fiber and high body mass index.In 2019,the top ten risk factors for colorectal cancer in Zhejiang Province were diet low in milk,diet low in whole grains,diet low in calcium,alcohol use,diet high in red meat,high body mass index,high fasting plasma glucose,low physical activi-ty,diet low in fiber and diet high in processed meat.Conclusions The disease burden of colorectal cancer in Zheji-ang Province showed an upward trend from 1990 to 2019.The top ten risk factors for colorectal cancer remained be-tween 1990 and 2019,while there was a slight change in ranking.
colorectal cancerdisease burdendisability-adjusted life yearsrisk factor
万方数据
维普
