Objective To investigate the factors affecting macular degeneration(MD)in middle-aged and elderly popula-tions,so as to provide the reference for prevention and treatment of MD.Methods People at ages of 50 years and old-er who were admitted to ophthalmology department of Hangzhou First People's Hospital and received MD screening were selected as the study subjects.General information including age,gender,eye-using habits and family history of MD were collected by questionnaire surveys.MD was diagnosed by ophthalmological examination,and the prevalence of MD in middle-aged and elderly people was analyzed.A multivariable logistic regression model was used to identify the influencing factors of MD.Results A total of 2 832 people were investigated,including 1 527 males(53.92%)and 1 305 females(46.08%),and 1 878 people(66.31%)aged 70 years and older.There were 498 people(17.58%)with good eye-using habits,1 180(41.67%)with general eye-using habits and 1 154(40.75%)with poor eye-using habits.There were 1 817 people with family history of MD(64.16%).Multivariable logistic regression analysis showed that peo-ple at ages of 70 years and older(OR=2.815,95%CI:1.350-5.871),with poor eye-using habits(OR=2.354,95%CI:1.373-4.035),with family history of MD(OR=2.782,95%CI:1.138-6.799),with cataract(OR=2.593,95%CI:1.157-5.815)and with visual central defect(OR=2.601,95%CI:1.252-5.404)had a higher risk of MD.Conclusion Age,eye-using habits,family history of MD,cataract and visual central defect are influencing factors for MD in middle-aged and elderly populations.
macular degenerationmiddle-aged and elderly populationsinfluencing factor