Objective To understand the pathogen spectrum composition of non-bacterial respiratory infections in Ping-hu City,Zhejiang Province,so as to provide insights for the prevention and control of respiratory infectious diseases.Methods A total of 592 throat or nasopharynx swab samples were collected from fever patients in Pinghu First Peo-ple's Hospital from Jamuary 2021 to November 2022.Multiple real-time fluorescence quantitative polymerase chain reac-tion was used to detect the nucleic acids of rhinovirus(RhV),respiratory syncytial virus(RSV),parainfluenza virus(PIV),adenovirus(ADV),metapneumovirus(MPV),coronavirus(CoV),Boca virus(Boca),enterovirus(EV),influenza vi-rus(Flu),chlamydia pneumoniae(CP)and mycoplasma pneumoniae(MP).The detection rates of pathogens and mixed in-fections in different age groups and seasons were analyzed.Results A total of 212 samples were tested positive for at least one pathogen's nucleic acid from 592 samples,with a total detection rate of 35.81％.The detection rates of RhV(9.80％),PIV(7.26％),Flu(6.76％),RSV(4.39％)and CoV(3.72％)were relatively high.The detection rates were high-er among patients at ages of 0 to 2 years and 3 to 17 years than among patients at ages of 18 to 59 years,and in au-tumn than in spring and winter(all P<0.05).Twenty-three samples were infected by mixed pathogens,accounting for 3.89％.The mixed infections were all detected two pathogens,with PIV,CoV,RhV,and ADV predominant.Conclu-sions From 2021 to November 2022,the main pathogens of non-bacterial respiratory infections in Pinghu City were RhV,PIV,FLu,RSV and CoV,and there were mixed infections.It is necessary to strengthen the prevention and con-trol of respiratory infection in infants and children.
万方数据
维普
