长效抗精神病药物治疗的精神分裂症病例分析
Characteristics of schizophrenic patients using long-acting antipsychotic medications
葛晓蕾 1张伟波 1陈春梅 1朱有为 1刘彦丽 1谢斌 2蔡军 2朱益1
作者信息
- 1. 上海交通大学医学院附属精神卫生中心防治科,上海 200030;上海交通大学中国医院发展研究院,上海 200030
- 2. 上海交通大学中国医院发展研究院,上海 200030;上海交通大学医学院附属精神卫生中心,上海 200030
- 折叠
摘要
目的 了解使用长效抗精神病药物治疗的精神分裂症病例特征,为长效抗精神病药物适用患者研究提供依据.方法 通过上海市精神卫生信息管理系统收集2020年6月—2022年6月上海市长效抗精神病药物治疗的精神分裂症病例资料,描述性分析人口学特征、患病和服药情况.结果 纳入长效抗精神病药物治疗的精神分裂症病例2 684例,年龄为(46.92±12.39)岁;男性1 246例,占46.42%;女性1 438例,占53.58%;无业1 397例,占52.05%;初中及以下学历1 429例,占53.24%;未婚1 301例,占48.47%;经济状况差832例,占31.00%;看护人以其父母为主,1 507例占56.15%.病程以≤10年和＞10～20年为主,各860例,占32.04%;自知力不全1 963例,占73.14%;住院次数≥1次1 570例,占58.49%.持续服药2 486例,占92.62%;服药方式以他人喂药为主,1 947例占72.54%;服药依从性以按时按量服药为主,2 437例占90.80%.结论 长效抗精神病药物治疗的精神分裂症病例以青壮年、未婚、无业、自知力不全、持续服药和他人给药为主要特征.
Abstract
Objective To investigate the characteristics of schizophrenic patients using long-acting antipsychotic medica-tions,so as to provide the basis for applicable population of long-acting antipsychotic medications.Methods Data of schizophrenic patients using long-acting antipsychotic medications in Shanghai City from June 2020 to June 2022 were collected through Shanghai Mental Health Information Management System,and demographic characteristics,illness and medication use of patients were descriptively analyzed.Results A total of 2 684 schizophrenic patients using long-act-ing antipsychotic medications were included in the study,had a mean age of(46.92±12.39)years,with 1 246 males(46.42%)and 1 438 females(53.58%).There were 1 397 unemployed cases,accounting for 52.05%;1 429 cases with an educational level in junior high school or below,accounting for 53.24%;1 301 unmarried cases,accounting for 48.47%;832 cases in poverty,accounting for 31.00%.The caregivers of patients were mainly their parents,with 1 507 cases accounting for 56.15%.The courses of illness were mainly≤10 years and>10-20 years,with 860 cases each,both accounting for 32.04%;1 963 cases with incomplete self-awareness,accounting for 73.14%;1 570 cases hospitalized at least once,accounting for 58.49%.There were 2 486 cases with continuous medication,accounting for 92.62%.The main method of taking medication was given by others,with 1 947 cases accounting for 72.54%.The medication adherence was mainly taking medication on time and in the right amount,with 2 437 cases accounting for 90.80%.Conclusion The main characteristics of schizophrenic patients using long-acting antipsychotic medications are young,unmarried,and unemployed adults,with incomplete self-awareness,continuous medication and medication given by others.
关键词
精神分裂症/长效抗精神病药物/服药依从性Key words
schizophrenia/long-acting antipsychotic medication/medication adherence引用本文复制引用
基金项目
上海市卫生健康委卫生行业临床研究专项(202040362)
上海市公共卫生体系建设三年行动计划重点学科建设项目(GWV-10.1-XK18)
上海市卫生健康委卫生健康政策研究课题(2023HP18)
上海交通大学医学院科技创新项目(WK2118)
上海市"医苑新星"青年医学人才培养计划(沪卫人事[2021]99号)
上海市加强公共卫生体系建设三年行动计划学科带头人项目(GWVI-11.2-XD25)
上海交通大学文科青年人才培育计划(2023QN038)
上海交通大学"医工交叉研究基金"重点项目(2024)(YG2024ZD24)
出版年
2024
NETL
NSTL
维普
万方数据