摘要
目的 系统评价我国女性产前抑郁检出率,为女性孕期心理保健提供参考.方法 检索中国知网、万方数据知识服务平台、维普中文科技期刊数据库和PubMed等数据库,收集建库至2023年7月30日发表的关于我国女性产前抑郁检出率的文献.采用Stata 17.0软件进行Meta分析;逐一剔除文献进行敏感性分析;采用漏斗图和Egger检验评价发表偏倚.结果 初步检索后获得文献5 687篇,最终纳入60篇,其中中文58篇,英文2篇;中等质量51篇,高质量9篇.总样本量为114 168人.Meta分析结果显示,产前抑郁总检出率为23.7%(95%CI:20.0%～27.5%);孕早、中、晚期抑郁检出率分别为22.1%(95%CI:15.5%～28.6%)、16.3%(95%CI:12.0%～20.6%)和19.9%(95%CI:16.0%～23.7%).东部、中西部地区产前抑郁总检出率分别为19.7%和27.5%;受教育程度为初中及以下、高中及以上女性产前抑郁总检出率分别为27.2%和17.9%,差异有统计学意义(均P＜0.05).敏感性分析显示Meta分析结果稳定性较好.产前抑郁总检出率、孕中期和孕晚期抑郁检出率结果可能存在发表偏倚.结论 我国女性产前抑郁总检出率为20.0%～27.5%,不同孕期产前抑郁检出率存在差异,孕早期检出率较高.
Abstract
Objective To systematically evaluate the detection rate of prenatal depression in Chinese women,so as to provide the reference for mental health care during pregnancy among women.Methods Publications pertaining to the detection rate of prenatal depression in Chinese women were retrieved from international and national databases from inception to July 30,2023,including CNKI,Wanfang Data,VIP,PubMed and other databases.The Stata 17.0 soft-ware was used for meta analysis,sensitivity analysis was performed using the leave-one-out method,and the publica-tion bias was evaluated using funnel plot and Egger's test.Results A total of 5 687 publications were retrieved,and 60 studies were finally included,with 58 in Chinese and 2 in English,51 of medium quality and 9 of high quality,and 114 168 participants.The results of meta-analysis showed that the overall detection rate of prenatal de-pression in Chinese women was 23.7%(95%CI:20.0%-27.5%).The detection rates of prenatal depression in the first,second and third trimesters were 22.1%(95%CI:15.5%-28.6%),16.3%(95%CI:12.0%-20.6%)and 19.9%(95%CI:16.0%-23.7%),in Eastern and Midwestern China were 19.7%and 27.5%,and in women with an education level of junior high school or below and high school or above were 27.2%and 17.9%,respectively,with statistically significant differences(all P<0.05).Sensitivity analysis showed that the study results were stable.There were publica-tion bias in the results of overall detection rate of prenatal depression,and detection rates in the second and third trimester.Conclusions The overall detection rate of prenatal depression in Chinese women ranges from 20.0%to 27.5%.There are differences in the detection rate of prenatal depression in different pregnancies,with the highest de-tection rate in the first trimester.
基金项目
中国学位与研究生教育学会研究课题(2020MS71)
山东省医药卫生科技发展计划(2017WS580)
教育部产学合作协同育人项目(201902104007)
潍坊医学院护理科研基金(2022MS005)
NETL
NSTL
维普
万方数据