摘要
目的 分析捐精志愿者各项精液质量参数,为男性不育防治及相关研究提供参考.方法 2021年1-3月采用方便抽样方法抽取浙江省人类精子库155名捐精志愿者为研究对象,通过问卷调查收集人口学资料;采集精液检测精液体积、精子浓度、精子总数、精子前向运动率和精子活力等参数,参考《世界卫生组织第5版人类精液检查实验室手册》评价精液质量合格情况.结果 155名捐精志愿者的年龄M(QR)为24(7)岁;未婚127人,占81.94%;无工作97人,占62.58%;本科及以上学历91人,占58.71%;体质指数≥25 kg/m2 42人,占27.09%.捐精志愿者的禁欲时间、精子总数、精液体积、精子浓度、精子前向运动率和精子活力的M(QR)分别为4(1)d、51(38)×106/1次射精、3.90(2.20)mL、204.60(161.30)×106/mL、47%(10%)和 50%(11%);不合格率分别为 0%、0.65%、1.29%、4.52%、9.68%和18.06%.总体精液质量不合格32人,不合格率为20.65%.结论 155名捐精志愿者中有20.65%总体精液质量不合格,以精子前向运动率和精子活力的不合格率相对较高.
Abstract
Objective To analyze the semen quality parameters of sperm donor volunteers,so as to provide insights into male infertility control and related research.Methods A total of 155 sperm donors were recruited from the Human Sperm Bank of Zhejiang Province using the convenience sampling method from January to March 2021.Demographic in-formation were collected through questionnaire surveys.Semen were collected,and parameters including semen volume,sperm concentration,total number of sperm,forward motility rate and total sperm viability were measured.Semen quali-ty was evaluated according to the WHO Laboratory Manual for the Examination and Processing of Human Semen.Re-sults Among 155 sperm donors,127 were unmarried(81.94%),97 were unemployed(62.58%),91 had a bachelor's de-gree and above(58.71%),and 42 had a body mass index of 25 kg/m2 and above(27.09%).The median age was 24(in-terquartile range,7)years.The median(interquartile range)abstinence time,total number of sperm,semen volume,sperm concentration,forward motility rate and total sperm viability were 4(1)d,51(38)×106/1 ejaculation,3.90(2.20)mL,204.60(161.30)×106/mL,47%(10%)and 50%(11%),and the unqualified rates were 0%,0.65%,1.29%,4.52%,9.68%and 18.06%,respectively.The overall unqualified rates of semen quality was 20.65%.Conclusion There were 20.65%of the 155 sperm donors with unqualified semen,and the unqualified rates of forward motility rate and total sperm viability were relatively high.
基金项目
浙江省基础公益研究计划项目(LTGY23H260008)
浙江省公共卫生与预防医学重点学科一流学科项目(A类)(KYYB202113)
杭州医学院研究生课程建设项目(26100548304-21)
浙江省医药卫生科技计划项目(2023KY664)
浙江省医药卫生科技计划项目(2023KY654)
NETL
NSTL
万方数据