Mediating effect of nighttime sleep duration on pain and frailty among elderly patients with comorbidity of chronic diseases
Objective To examine the mediating effect of nighttime sleep duration on pain and frailty among elderly pa-tients with comorbidity of chronic diseases,so as to provide insights into frailty control among the elderly.Methods Demographic information,pain and nighttime sleep duration of the elderly at ages of 60 years and older were collected from the China Health and Retirement Longitudinal Study 2020.Frailty were evaluated using frailty index.The mediat-ing effect of sleep duration for pain and frailty was analyzed using the Process program compiled by HAYSS and col-leagues,and the significance of the mediating role was tested using the Bootstrap test.Results A total of 2 246 elder-ly patients with comorbidity of chronic diseases were enrolled,including 1 195 males(53.21%)and 1 051 females(46.79%),with a median age of 65.00(interquartile range,8.00)years.There were 504 cases with frailty(22.44%),with a median pain score of 0(interquartile range,1.00)points,and a mean nighttime sleep duration of(6.44±1.55)hours.Mediating analysis showed that pain affected frailty directly and positively with the effect value of 0.089(95%CI:0.066-0.112),and also affected frailty by nighttime sleep duration directly and positively with the effect value of 0.047(95%CI:0.036-0.058),with the mediating effect contributed 34.56%of the total effect.Conclusion Pain can directly or indirectly affect frailty among elderly patients with comorbidity of chronic diseases through nighttime sleep duration.
the elderlycomorbidity of chronic diseasespainnighttime sleep durationfrailty
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