老年慢性病共病患者夜间睡眠时长在疼痛与衰弱间的中介效应分析
Mediating effect of nighttime sleep duration on pain and frailty among elderly patients with comorbidity of chronic diseases
李思琦 1曾洋菁 1王雪娇 2琚新梅1
作者信息
- 1. 海南医科大学国际护理学院,海南 海口 571199
- 2. 海南医科大学第一附属医院,海南 海口 570102
- 折叠
摘要
目的 探讨夜间睡眠时长在老年慢性病共病患者疼痛与衰弱间的中介效应,为老年人衰弱防制提供依据.方法 通过2020年中国健康与养老追踪调查数据库,收集患2种及以上慢性病≥60岁老年人的人口学信息、疼痛程度和夜间睡眠时长等资料,采用衰弱指数评估衰弱情况.采用HAYES等编译的Process程序分析夜间睡眠时长在疼痛与衰弱间的中介效应,并采用Bootstrap法检验中介效应的显著性.结果 收集2 246例老年慢性病共病患者资料,其中男性1 195例,占53.21%;女性1 051例,占46.79%.年龄M(QR)为65.00(8.00)岁.衰弱504例,占22.44%;疼痛得分M(QR)为0(1.00)分;夜间睡眠时长为(6.44±1.55)h.中介效应分析结果显示,老年慢性病共病患者疼痛直接正向影响衰弱,效应值为0.089(95%CI:0.066～0.112),也通过夜间睡眠时长间接正向影响衰弱,效应值为0.047(95%CI:0.036～0.058),中介效应对总效应的贡献率为34.56%.结论 老年慢性病共病患者疼痛可直接或通过夜间睡眠时长间接影响衰弱.
Abstract
Objective To examine the mediating effect of nighttime sleep duration on pain and frailty among elderly pa-tients with comorbidity of chronic diseases,so as to provide insights into frailty control among the elderly.Methods Demographic information,pain and nighttime sleep duration of the elderly at ages of 60 years and older were collected from the China Health and Retirement Longitudinal Study 2020.Frailty were evaluated using frailty index.The mediat-ing effect of sleep duration for pain and frailty was analyzed using the Process program compiled by HAYSS and col-leagues,and the significance of the mediating role was tested using the Bootstrap test.Results A total of 2 246 elder-ly patients with comorbidity of chronic diseases were enrolled,including 1 195 males(53.21%)and 1 051 females(46.79%),with a median age of 65.00(interquartile range,8.00)years.There were 504 cases with frailty(22.44%),with a median pain score of 0(interquartile range,1.00)points,and a mean nighttime sleep duration of(6.44±1.55)hours.Mediating analysis showed that pain affected frailty directly and positively with the effect value of 0.089(95%CI:0.066-0.112),and also affected frailty by nighttime sleep duration directly and positively with the effect value of 0.047(95%CI:0.036-0.058),with the mediating effect contributed 34.56%of the total effect.Conclusion Pain can directly or indirectly affect frailty among elderly patients with comorbidity of chronic diseases through nighttime sleep duration.
关键词
老年人/慢性病共病/疼痛/夜间睡眠时长/衰弱Key words
the elderly/comorbidity of chronic diseases/pain/nighttime sleep duration/frailty引用本文复制引用
基金项目
海南省自然科学基金高层次人才项目(821RC566)
海南省哲学社会科学规划课题项目(RZ2300005753)
出版年
2024
NETL
NSTL
万方数据