Age-period-cohort analysis of the incidence of hepatitis B among children aged under 10 years in Zhejiang Province from 2004 to 2020
Objective To investigate the trend of hepatitis B incidence among children under 10 years in Zhejiang Prov-ince from 2004 to 2020 with age,period and birth cohort,so as to provide the basis for evaluating the implementation of hepatitis B prevention and control measures for children in Zhejiang Province.Methods Data of hepatitis B inci-dence among children under 10 years in Zhejiang Province from 2004 to 2020 were collected through the Infectious Dis-ease Reporting Information System of Chinese Disease Prevention and Control Information System.The trend in hepatitis B incidence was analyzed using an age-period-cohort model.Results The incidence of hepatitis B among children un-der 10 years in Zhejiang Province decreased from 12.91/105 in 2004 to 0.61/105 in 2020,with a reduction of 95.24%.The incidence showed an decreasing trend with the increase of age.Compared with 2012,the risk of hepatitis B inci-dence among children under 10 years appeared a tendency towards a decline with time,with the period rate ratio de-creased from 4.546(95%CI:3.322-6.220)in 2004 to 0.277(95%CI:0.161-0.478)in 2020.Compared with the 2008 co-hort,the risk of hepatitis B incidence appeared a tendency towards a decline with cohort,with the cohort rate ratio de-creased from 25.535(95%CI:15.105-43.166)in 1995 to 0.135(95%CI:0.038-0.475)in 2020.Conclusions The inci-dence of hepatitis B among children aged under 10 years in Zhejiang Province from 2004 to 2020 showed a downward trend.The risk of hepatitis B incidence decreased with increasing age and advancing birth cohort.
万方数据
维普
