Objective To investigate the mortality and life loss of female breast cancer in Wenzhou City,Zhejiang Prov-ince from 2014 to 2022,so as to provide the evidence for prevention and control of breast cancer.Methods Data of female breast cancer deaths in Wenzhou City were collected through the Wenzhou Chronic Disease Monitoring and Man-agement information System from 2014 to 2012.The mortality of breast cancer was calculated,and standardized by the data from the Sixth Chinese National Population Census in 2010(Chinese-standardized rate)and the world standard pop-ulation first introduced by Segi(world-standardized rate).The life loss were measured using potential years of life lost(PYLL),rate of potential years of life lost(PYLLR)and average years of life lost(AYLL).The trends in mortality,PYLLR and AYLL were analyzed using the average annual percent change(AAPC).Results Totally 2 523 deaths were reported due to breast cancer from 2014 to 2022,ranking fifth in the order of female malignant tumor deaths.The crude mortality of female breast cancer was 7.13/105,showing an increasing trend with AAPC of 2.186%(P<0.05).The Chinese population-standardized mortality and global population-standardized mortality were 5.93/105 and 4.39/105,show-ing no significant trend with AAPC of-0.617%and-0.602%(both P>0.05),respectively.The crude mortality of fe-male breast cancer appeared a tendency towards a rise with age(P<0.05).The crude mortality of breast cancer in fe-males aged 65 years and older showed an increasing trend(AAPC=3.283%,P<0.05),but there were no significant ten-dency aged 15 to<45 years and 45 to<65 years(AAPC=-1.011%and-1.850%,both P>0.05).The PYLL,PYLLR and AYLL of breast cancer were 41 227.50 person-years,1.23‰ and 19.44 years per person,respectively.AYLL showed a decreasing trend(AAPC=-1.969%,P<0.05),and PYLLR showed no significant trend(AAPC=-0.527%,P>0.05).Conclusions The mortality of female breast cancer in Wenzhou City appeared a tendency towards a rise from 2014 to 2022,and AYLL appeared a downward trend.Females aged 65 years and older were the key groups for the prevention and control of breast cancer.
breast cancermortalitylife lossaverage annual percent change
万方数据
维普
