摘要
目的 分析2013-2021年上海市宝山区居民结直肠癌筛查结果,为完善结直肠癌筛查和防治策略提供依据.方法 选择2013-2021年宝山区50～74岁常住居民为筛查对象,采用危险度评估表和粪便隐血检测进行初筛,危险度评估阳性或粪便隐血检测阳性为初筛阳性,初筛阳性者进行结肠镜检查;分析初筛阳性率、结肠镜检查依从率和结肠镜检查结果.结果 2013-2021年宝山区完成结直肠癌初筛264 907人,初筛阳性65 333人,初筛阳性率为24.66%,其中危险度评估阳性率为12.16%,粪便隐血阳性率为14.64%.14 473人完成结肠镜检查,依从率为22.15%.检出癌前病变1 284例,检出率为8.87%;结直肠癌386例,检出率为2.67%.男性初筛阳性率、结肠镜检查依从率、癌前病变检出率和结直肠癌检出率分别为25.55%、23.12%、11.60%和3.62%,高于女性的24.06%、21.45%、6.74%和1.93%(均P<0.05).随着年龄增长,初筛阳性率呈上升趋势,结肠镜检查依从率呈下降趋势,癌前病变检出率和结直肠癌检出率呈上升趋势(均P<0.05).2013-2021年居民初筛阳性率呈下降趋势,结肠镜检查依从率呈上升趋势(均P<0.05).结论 2013-2021年宝山区结直肠癌癌前病变检出率为8.87%,结直肠癌检出率为2.67%,男性和高龄人群是筛查重点人群,居民结肠镜检查依从性有待提高.
Abstract
Objective To analyze the results of colorectal cancer screening among residents in Baoshan District,Shang-hai Municipality from 2013 to 2021,so as to provide the basis for promoting colorectal cancer screening and preven-tion.Methods Permanent residents aged 50 to 74 years in Baoshan District from 2013 to 2021 were selected as the screening population.The initial screening was conducted using a risk assessment form and fecal occult blood test.Posi-tive results on either the risk assessment form or fecal occult blood test were considered positive for the initial screen-ing.Participants with positive initial screening results were invited to undergo colonoscopy.The positive rate of the ini-tial screening,colonoscopy compliance rate,and colonoscopy results were analyzed.Results A total of 264 907 individ-uals underwent the initial colorectal cancer screening in Baoshan District from 2013 to 2021,with 65 333 individuals(24.66%)testing positive.Among them,the positive rate of the risk assessment form was 12.16%,and the positive rate of fecal occult blood test was 14.64%.A total of 14 473 individuals completed colonoscopy,with a compliance rate of 22.15%.A total of 1 284 precancerous lesions were detected,with a detection rate of 8.87%,and 386 cases of colorec-tal cancer were identified,with a detection rate of 2.67%.The positive rate of the initial screening,colonoscopy compli-ance rate,precancerous lesion detection rate,and colorectal cancer detection rate were higher in males than in females(25.55%vs.24.06%,23.12%vs.21.45%,11.60%vs.6.74%,3.62%vs.1.93%,all P<0.05).With increasing age,the positive rate of the initial screening increased,the colonoscopy compliance rate decreased,the precancerous lesion detec-tion rate and colorectal cancer detection rate increased(all P<0.05).From 2013 to 2021,the positive rate of the initial screening among residents showed a downward trend,while the colonoscopy compliance rate showed an upward trend(both P<0.05).Conclusions The detection rate of precancerous lesions in colorectal cancer was 8.87%,and the detec-tion rate of colorectal cancer was 2.67%in Baoshan District from 2013 to 2021.Male and older individuals were the key populations for screening,and the colonoscopy compliance among residents needs to be improved.
基金项目
上海市宝山区医学重点专科项目(B类)(BSZK-2023-BZ14)
NETL
NSTL
万方数据