Multimodal non-pharmacological interventions for Alzheimer's disease:a review
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and behavioral impairments.Currently,the treatment mainly relies on pharmacotherapy,yet its effectiveness is limited and accompanied by adverse reactions.Multimodal non-pharmacological interventions (MNPI),which combine two or more non-pharmacological intervention approaches,can synergistically improve cognitive function,neuropsychiatric symp-toms,activities of daily living,and quality of life in AD patients,and offers advantages of safety,cost-effectiveness and simplicity.This article reviews MNPI-related literature published domestically and internationally from 2018 to 2024,and focuses on the application of cognitive training,physical activity,and other combined intervention methods in MN-PI,providing the reference for developing personalized interventions for AD.
Alzheimer's diseasemultimodal non-pharmacological interventionscognitive function
万方数据
维普
