Effect observation of preoperative low-dose dexamethasone on the prevention of pharyngeal discomfort after thyroidectomy
Objective To evaluate the role of a small single dose of dexamethasone preoperative application for the prevention of post-thyroidectomy pharyngeal discomfort.Methods Two hundred and ten patients admitted to the General Surgery Department of Lishui Central Hospital in Zhejiang Province from March 2020 to March 2021 were selected for the study.They were divided into experimental and control groups,with the experimental group being the dexamethasone group(n=105)and the control group being the saline group(n=105).In the experimental group,dexamethasone 10 mg+saline 100 mL was administered half an hour before surgery,and in the control group,the same volume of saline was administered at the same time point.The occurrence of pharyngeal discomfort in the two groups of patients after thyroid surgery was compared.Results The visual analogue score of postoperative nausea and vomiting,cough and swallowing pain in the experimental group were significantly lower than those in the control group,and the differences were all statistically significant(all P<0.001);the postoperative hospitalization-related indexes(including the amount of postoperative drainage fluid,hospitalization time and hospitalization cost)in the experimental group were significantly better than those in the control group,and the differences were all statistically significant(all P<0.001);the age,gender,height,weight,surgical method,postoperation blood calcium and incision healing in the two groups were compared,and the differences were not statistically significant(all P>0.05).Conclusions Preoperative injection of single-low-dose dexamethasone in patients undergoing thyroidectomy can reduce the incidence of postoperative nausea and vomiting,cough,and painful swallowing.
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