Research Progress on Gene Polymorphisms Related to Osteosarcoma
Osteosarcoma,which primarily affects children and adolescents,is a highly malignant bone tumor with high rates of disability and mortality.Therefore,the exploration of biological markers related to its occurrence,development,and prognosis is crucial.Genome-wide association studies have revealed the vital role of genetic polymorphisms in the pathogenesis of osteosarcoma.This study aims to provide new insights into reliable biomarkers of osteosarcoma through the analysis of the functional single-nucleotide polymor-phisms of tumor-related genes.
OsteosarcomaSusceptibilitySingle nucleotide polymorphismsBiomarkersGenome-wide asso-ciation study
国家科技期刊平台
NSTL
万方数据
