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结直肠癌免疫治疗的现状及研究进展

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结直肠癌(CRC)的高发病率和死亡率严重威胁着人们的健康与生命安全.手术联合放化疗是目前结直肠癌的主要治疗方式,然而其结果不尽如人意.免疫治疗的出现给结直肠癌患者带来了曙光.以免疫检查点抑制剂为主的免疫治疗为部分患者带来获益.除此之外,新兴的肿瘤疫苗、过继性细胞治疗等也取得了显著的结果.本文就结直肠癌免疫治疗的现状及研究进展进行综述.
Current Status and Research Progress of Immunotherapy for Colorectal Cancer
Colorectal cancer (CRC) seriously threatens people's health and safety,with high incidence and mortality rates. Surgery combined with radiotherapy and chemotherapy is the main treatment method for CRC at present,but the results are unsatisfactory. The emergence of tumor immunotherapy has brought hope to patients with CRC. Immunotherapy based on immune checkpoint inhibitors provides benefits to some patients. In addition,emerging tumor vaccines and adoptive cell therapy have achieved significant results. This paper reviews the current status and progress of immunotherapy for CRC.

Colorectal cancerImmunotherapyCancer vaccinesAdoptive cell therapyImmune checkpoint inhibitors

张湘晨、梁新军、魏少忠

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430079 武汉,华中科技大学同济医学院附属湖北肿瘤医院胃肠外科

结直肠癌 免疫治疗 肿瘤疫苗 过继性细胞治疗 免疫检查点抑制剂

2024

肿瘤防治研究
湖北省卫生厅,中国抗癌协会,湖北省肿瘤医院

肿瘤防治研究

CSTPCD
影响因子:0.737
ISSN:1000-8578
年,卷(期):2024.51(11)