摘要
目的 分析18氟-脱氧葡萄糖-正电子发射型计算机体层扫描-计算机断层扫描仪(18F-FDGPET-CT)在胃肠道恶性肿瘤诊断及术后随访中的应用价值.方法 39例怀疑胃肠道恶性肿瘤的患者均行全身18F-FDG PET-CT检查,并经手术或术后病理结果及随访确诊.结果 18F-FDG PET-CT显像对胃肠道恶性肿瘤原发病灶检出的灵敏度、特异度均为100.0％,在胃癌中对于转移灶的灵敏度、特异度、准确度分别为80.0％(4/5)、90.9％(10/11)、87.5 ％(14/16),对结直肠癌转移灶的灵敏度、特异度、准确度分别为88.9％(8/9)、92.9％(13/14)、91.3％(21/23).PET-CT诊断胃癌局部淋巴结转移的灵敏度、特异度、准确度分别为50.0％(3/6)、90.0％(9/10)、75.0％(12/16),诊断结直肠癌局部淋巴结转移的灵敏度、特异度、准确度分别为71.4％(5/7)、93.8％(15/16)、87.0％(20/23).结论 18F-FDGPET-CT对胃肠道恶性肿瘤的术前诊断及分期有重要价值,优于传统检查方法.
Abstract
Objective To explore 18F-FDG PET-CT in the detection of malignant tumors of the gastrointestinal tract.Methods 39 patients with gastrointestinal tumors who was diagnosed with operation,pathological examination,clinical and imaging follow-up undertake the whole-body 18F-FDG PET-CT.Results The sensitivity and specificity were both 100.0 ％ for primary malignant tumors.Gastric metastases sensitivity,specificity and accuracy were 80.0 ％ (4/5),90.9 ％ (10/11),87.5 ％ (14/16),and the colorectal metastases sensitivity,specificity,accuracy of diagnostic results were 88.9 ％ (8/9),92.9 ％ (13/14),91.3 ％ (21/23).The gastric cancer lymph node metastasis sensitivity,specificity and accuracy were 50.0 ％ (3/6),90.0 ％ (9/10),75.0 ％ (12/16),in the diagnosis of colorectal local lymph node metastasis the sensitivity,specificity and accuracy were 71.4 ％ (5/7),93.8 ％ (15/16),87.0 ％ (20/23).Conclusion The 18F-FDG PET-CT imaging for gastrointestinal malignant tumor diagnosis and residual lesions recurrence or lesions metastases of detection is of important value and better than traditional examination methods.
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