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中药活性肽发现方法研究进展

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中药是天然药物和活性前体的丰富来源,除小分子成分外,近年来其中的活性肽/蛋白质也备受关注.快速发展的分离和纯化技术,结合先进的筛选、鉴定策略,使越来越多具有药用价值的生物活性肽被发现并报道.本文综述了近年来活性肽的发现流程和筛选新方法,旨在为研究和发现中药活性肽提供参考.
Advances in discovery of active peptides from traditional Chinese medicine
As a rich source of natural medicine and active precursor,traditional Chinese medicine has received increasing attention because of natural active peptides/proteins besides small molecular components.With the rapid development of separation and purification technologies and advanced screening and identification strategies,more biologically active peptides with medicinal value have been discovered and reported.This article reviewed the discovery and screening methods for active peptides in recent years,aiming to provide reference for the research and discovery of active peptides in traditional Chinese medicine.

traditional Chinese medicinepolypeptideseparation and purificationactive peptide screening

王鸿杰、王锐、高雯

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中国药科大学中药学院,南京 211198

中药 多肽 分离纯化 活性肽筛选

山东省重点研发计划项目2022年度江苏省高校"青蓝工程"优秀青年骨干教师培养对象项目

2021CXGC010507

2024

中南药学
湖南省药学会

中南药学

CSTPCD
影响因子:0.736
ISSN:1672-2981
年,卷(期):2024.22(1)
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