Research progress of Toll-like receptors in coronary heart disease and target drug analysis
Coronary heart disease(CHD)is a cardiovascular disease characterized by chronic inflammatory stimulation and plaque accumulation,which seriously threatens the lives of thousands of patients.It has been found that Toll-like receptors(TLRs)participate in the production of many inflammatory factors by mediating the immune activation,and play a complex bidirectional regulatory role in the occurrence and development of CHD.Treatment with targeted TLRs has a potential anti-atherosclerotic effect.This article reviewed the mechanism of TLRs signaling in CHD and the latest research progress in TLRs-related anti-atherosclerotic drugs.
coronary heart diseaseToll-like receptorimmunityinflammationtarget drug
万方数据
维普
