β-sitosterol is the main active ingredient of Angelica sinensis and other medicinal plants.It has antioxidant,cell cycle-regulating,apoptosis-promoting,and anti-inflammation effects.β-sitosterol can potentially play a therapeutic role in breast cancer by regulating signaling pathways such as estrogen,Wnt/β-catenin,PI3K/Akt,MAPK/ERK,and NF-κB.This study aims to elucidate the mechanism of β-sitosterol in the treatment of breast cancer and provide a theoretical basis for the clinical application and new drug development.
关键词
β-谷甾醇/信号通路/乳腺癌/作用机制
Key words
β-sitosterol/signaling pathway/breast cancer/mechanism of action
维普
万方数据