Odor differential markers for different processed products of Pinelliae Rhizoma by electronic nose combined with network pharmacology
Objective To obtain the odor fingerprint information of different processed products of Pinelliae Rhizoma with Heracles Ⅱ ultra-fast gas phase electronic nose,and to analyze the odor differential markers of different processed Pinelliae Rhizoma products combined with network pharmacology.Methods Heracles Ⅱ ultra-fast gas phase electronic nose was used to obtain the gas chromatograms of different processed products of Pinelliae Rhizoma.Multivariate analysis was used to obtain the odor differential markers for products.Combined with network pharmacology,the targets and pathways of different components were obtained,and the potential odor differential markers of products of Pinelliae Rhizoma were predicted.Results Totally 21 odor related chemical components were identified in the processed products of Pinelliae Rhizoma.Among them,five components such as methyleugenol and diethyl ketone were the odor differential markers,and network pharmacological analysis showed that these components had anti-cough and anti-inflammation effects.Conclusion The odor fingerprint of Pinelliae Rhizoma and its processed products are highly specific,and five chemical components could be used as potential odor differential markers for processed products of Pinelliae Rhizoma.This study provides new ideas for the research on the mechanism and processing technology of traditional Chinese medicine.
万方数据
维普
