Seco-lanostane constituents from Poria cum Pini Radix
Objective To determine the chemical constituents of seco-lanostane in Poria cum Pini Radix.Methods The seco-lanostanes were separated and purified with a variety of chromatographic techniques as silica gel column,RP-18 medium pressure column,Sephadex LH-20 column,and preparative HPLC,and identified by NMR and MS spectroscopy.Results Totally 11 seco-lanostanes were isolated from Poria cum Pini Radix,and identified as poricoic acid B(1),poricoic acid A(2),poricoic acid DM(3),16α,27-dihydroxy-3,4-secolanosta-4(28),8(9),24-triene-3,21-dioic acid(4),poricoic acid ZC(5),poricoic acid ZM(6),poricoic acid E(7),poricoic acid D(8),poricoic acid ZG(9),poricoic acid M(10)and poricoic acid L(11).Conclusion Compounds 4～6 and 9～11 have been obtained from the Poria cum Pini Radix for the first time.
Poria cum Pini Radixseco-lanostanechemical constituentstructural identification
万方数据
维普
