Research advance in cardiotoxicity induced by anthracyclines
Anthracyclines are among the most effective chemotherapeutic drugs in anti-tumor therapy because of their broad anti-tumor spectrum,strong action and high efficacy.However,anthracyclines may also cause many adverse reactions,such as cardiotoxicity,hepatorenal toxicity,myelosuppression,and hand-foot syndrome.Among these,cardiotoxicity is the most serious adverse reaction,and greatly affects the survival rate and quality of life of cancer patients and restricts their clinical application.Therefore,how to monitor and mitigate their cardiotoxicity at an early stage has become an urgent clinical problem.This paper aims to discuss the mechanism of action,early monitoring and progress in the prevention of cardiotoxicity induced by anthracycline antitumor drugs.
万方数据
维普
