Effect of nutrition support status on the clinical outcome of critically ill patients
Objective To determine the impact of state of nutritional support on nutritional indicators and clinical outcomes in critically ill patients.Methods A single-center retrospective cohort study was conducted.Patients admitted to the ICU of Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University from January to June 2022 who were eligible for enrollment were selected retrospectively.The impact of nutritional support status of critically ill patients on clinical outcome was determined.Results Totally 126 critically ill patients(35 females and 91 males)aged(63.93±18.78)years were included.The SOFA score and APACHE-Ⅱ score of patients were(6.62±4.11)and(20.92±7.51),respectively.Altogether 91(72.2％)patients were at high nutritional risk(NUTRIC score≥6)and 35(27.8％)patients were at low nutritional risk(NUTRIC score＜6).Totally 111(88.1％)patients received nutritional support.Of the 86 patients who received enteral nutrition,55(64.0％)received early enteral nutrition support at≤48 h of admission.Of the 111 patients who had nutritional support,23 patients(20.7％)showed both energy and protein compliance at≤72 h of admission.The total length of hospital stay was longer in the high-nutritional-risk group(P＜0.05),and the 28-day mortality rate in the early enteral nutrition group was lower(P＜0.01);the change in the serum albumin within 7 days of admission was greater(P＜0.05)for patients in the early protein adequacy group.Conclusion Early enteral nutritional support within 48 h of admission is recommended for patients with ICU stay longer than 48 h.Early enteral nutritional support reduces the 28-day mortality;early protein or energy adequacy has little effect on clinical outcome of patients in the ICU.
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