首页|中药抗电离辐射药理作用及机制研究进展

中药抗电离辐射药理作用及机制研究进展

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中药具有高效、低毒、多靶点、特异性强等特点,其在辐射防护方面有着独特的优点.基于辐射对机体中免疫系统、造血系统和生殖系统的相关细胞及其通路损伤,以及DNA损伤和抗氧化应激,本文论述了近十年来中药及其复方抗辐射药理作用及机制的研究进展,并提出现有研究存在的问题,以期为后续新型辐射防护剂的中药产品开发提供参考.
Research progress in pharmacological action and mechanism of Chinese medicine against ionizing radiation
Traditional Chinese medicine is characterized by its high efficiency,low toxicity,multiple targets and strong specificity,as well as its unique advantages in radiation protection.Based on radiation damage to cells and their pathways in the immune system,hematopoietic system and reproductive system,as well as DNA damage and antioxidant stress,this paper reviewed recent research progress in the pharmacological action and mechanism of anti-radiation in traditional Chinese medicine.Chinese medicine compounds over the past decades are reviewed and the existing problems are presented to provide a reference for the development of new radiation protection agents in Chinese medicine products.

traditional Chinese medicineanti-radiationpharmacological actionmechanism of actionresearch progress

王帅、李航、王闯闯、赵孟楠、李祎亮、侯文彬、周福军

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天津中医药大学,天津 301617

北京协和医学院&中国医学科学院放射医学研究所,天津市放射医学与分子核医学重点实验室,天津 300192

天津药物研究院,天津 300462

中药 抗辐射 药理作用 作用机制 研究进展

国家自然科学基金国家自然科学基金中国医科院医学与健康科技创新工程重大协同创新项目

82104012822029502021-I2M-1-042

2024

中南药学
湖南省药学会

中南药学

CSTPCD
影响因子:0.736
ISSN:1672-2981
年,卷(期):2024.22(3)
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