Chemical constituents of steroidal saponins from Paris polyphylla var.yunnanensis
Objective To determine the steroidal saponin constituents in rhizomes of Paris polyphylla var.yunnanensis.Methods C-18 silica gel column chromatography and semi-preparative HPLC were used to isolate and purify the 70％ethanol extract from the rhizomes of Paris polyphylla var.yunnanensis.The structures of the isolated compounds were determined by extensive spectroscopic analysis and chemical methods.Results Six compounds were isolated and identified as parisyunnanoside Ⅰ(1),paristenoside B(2),26-O-β-D-glucopyranosyl-3β,16a,26-trihydroxy-(23R,25R)-16,23-cyclocholest-5,17(20)-dien-22-one-3-O-a-L-arabinofuranosyl-(1 → 4)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-glucopyranoside(3),26-O-β-D-glucopyranosyl-17,22-dihydroxy-(25R)-furost-5-en-3-O-α-L-rhamnopyranosyl-(1 → 2)-β-D-glucopyranoside(4),parisyunnanoside A(5),and 26-O-β-D-glucopyranosyl-3β,26-dihydroxy-(25R)-cholesta-5,17(20)-dien-16,22-dione-3-O-α-L-rhamnopyranosyl-(1 → 4)-[α-L-rhamnopyranosyl-(1 → 2)]-β-D-glucopyranoside(6).Conclusion Compounds 3,4 and 6 have been isolated from the rhizomes of Paris polyphylla var.yunnanensis for the first time.
Paris polyphylla var.yunnanensissaponinchemical constituent
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