Advances in the study of ferroptosis in pancreatic diseases
Ferroptosis,a novel mode of cell death regulation,has gathered much attention from domestic and international scholars in recent years.This mechanism of cell death exacerbates the progression of pancreatitis and enhances the sensitivity of pancreatic cancer to chemotherapeutic drugs,especially gemcitabine.This article aims to summarize the research progress and related mechanisms of ferroptosis in pancreatic diseases both domestically and internationally,and provide a direction for the prevention and treatment of pancreatic diseases.Moreover,it also provides suggestions to critical issues,optimizing the application of ferroptosis in the prevention and treatment of pancreatic diseases.