Objective To determine the chemical constituents of Pachysandra terminalis Sieb.et Zucc..Methods The separation and purification were conducted by silica gel column chromatography,gel column chromatography and semi-preparative liquid chromatography.The structural was analyzed by combining its physicochemical properties and spectroscopic techniques such as NMR,IR and MS.Results Ten compounds were isolated from 80％ethanol extract of Pachysandra terminalis and identified as(+)-syringaresinol(1),benzoic acid(2),4-hydroxy benzaldehyde(3),4-hydroxyacetophenone(4),vanillic acid(5),syringaldehyde(6),4-hydroxy-3,5-dimethoxyacetophenone(7),3,4,5-trimethoxylbenzoic acid(8),3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl)-1-propanone(9),and schumannione(10).Conclusion Compounds 1～4,and 7～10 have been isolated for the first time from Pachysandra.
Pachysandra terminalisextraction and isolationchemical compositionstructural characterizationlignanphenol
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