摘要
天麻素最早分离自植物天麻的根茎,现临床主要用于治疗中枢系统相关疾病.现代药理学研究表明天麻素具有保护神经细胞及其功能、调节血管、抗炎、抗肿瘤和调节骨代谢等多种作用.临床研究证实,天麻素用于治疗精神失常、癫痫、偏头痛、脑梗死、眩晕等疾病疗效明显,且具有多靶点、多途径的特点.本文对近年来天麻素的药理作用和临床应用方面的研究进行综述,以期为开发新型天麻素相关治疗药物提供参考.
Abstract
Gastrodin was first isolated from the rhizome of Gastrodia elata Bl,while currently it is used in clinical practice for central nervous system-related diseases.Modern pharmacological studies have shown that gastrodin has many effects,such as protecting the nerve cells and their function,regulating blood vessels,anti-inflammation,and anti-tumor effect,and regulating bone metabolism.Clinical studies have proved that gastrodin is effective for mental disorders,epilepsy,migraine,cerebral infarction,vertigo and other diseases.Gastrodin has the characteristics of multi-target and multi-pathway.This article reviewed the pharmacological effects and clinical applications of gastrodin in recent years to provide reference for the development of gastrodin related therapeutic drugs.
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