Basis and clinical progress in mesenchymal stem cells for acute lung injury caused by sepsis
Sepsis acute lung injury is a life-threatening disease with high morbidity and mortality,which is a major difficulty in clinical treatment.There are limitations of traditional treatment methods,so it is urgent to find new therapeutic approaches.Mesenchymal stem cell therapy,as a potentially effective cellular treatment,has attracted much attention.Studies have shown that mesenchymal stem cell therapy has potential therapeutic effects on human patients and is relatively safe.However,there remain some challenges and questions,such as the origin and preparation of mesenchymal stem cells,the best treatment regimen,and the mechanism of treatment.This review summarized the mechanism of mesenchymal stem cell therapy for sepsis-induced acute lung injury,research,and challenges in clinical application,aiming to better understand the prospect of mesenchymal stem cell therapy for sepsis-induced acute lung injury,and provide new ideas for clinical practice.
mesenchymal stem cellacute lung injurytreatment strategyclinical research progress
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