Research progress in functionalized nanodiamond-related drug delivery for antitumor applications
In Compendium of Materia Medica,diamond has been mentioned for the treatment of burns and scalds.Modern medical research shows that diamond(especially nanodiamond)displays excellent biocompatibility,minimal toxicity,outstanding physical and chemical stability,superhardness,high thermal conduction,high surface activity,and easy functionalization,etc.Nanodiamonds combined with various chemical drugs and/or nucleic acid drugs are favorable for highly efficient drug delivery in antitumor treatments.This review,based on functionalized nanodiamonds,summarized the current achievements in biomedical applications for the antitumor treatment of leukemia,colon cancer,lung cancer,liver cancer,breast cancer and pancreatic cancer,etc.,aiming to provide new ideas clinical practice.
NETL
NSTL
万方数据
