Biomedical applications of layered double hydroxides delivery system with different metal compositions
Layered double hydroxide is a two-dimensional layered nanomaterial composed of positively charged metal ion hydroxide layer and intercalated anion,which is widely used in environmental treatment and other fields.Owing to simple preparation,high flexibility of composition,high drug loading rate,pH responsive release,good biocompatibility and safety,layered double hydroxides have gradually been used in anti-tumor therapy.This paper reviewed the application of layered double hydroxides composed of different metal ions in biomedicine fields and discussed further application and possible challenges in clinical conversion,hoping to provide reference for the development of layered double hydroxides drug delivery system.
layered double hydroxidemetal compositionsynergistic therapymagnetic resonance imagingtumor diagnosis and treatment