Research progress in the mechanism of traditional Chinese medicine and natural products for hyperuricemia and gout
Hyperuricemia is a metabolic disorder characterized by elevated levels of uric acid,which is associated with increased production or decreased excretion of uric acid.Hyperuricemia is not only the main factor for gout,but also closely related to the occurrence and development of diseases such as hypertension,atherosclerosis,and chronic kidney diseases.The clinical treatment of hyperuricemia and gout with drugs has been effective,but long-term use may cause adverse reactions in patients.Traditional Chinese medicine and natural products,owing to their multi-targets and high safety,may effectively control the occurrence and development of gout.We comprehensively reviewed the mechanism of traditional Chinese medicine and natural products for hyperuricemia and gout,aiming to provide insights for the development of safe and effective drugs to prevent and treat hyperuricemia and gout.