Establishment of drug use evaluation criteria for tofacitinib tablets and application
Objective To establish the drug use evaluation(DUE)standard for tofacitinib tablets and provide a reference for the rationally clinical use of tofacitinib tablets.Methods Based on tofacitinib drug label,expert consensus on related guidelines and clinical research,DUE criteria for tofacitinib tablet were developed.The outpatient and emergency prescriptions of tofacitinib tablets from January 1,2021 to September 30,2023 in a Grade Ⅲ Hospital were retrospectively analyzed.Results Totallly 1086 prescriptions were included,the compliance rate of medication indications was 93.6％,and the compliance rate of usage and dosage reached 93.6％.Potential drug-drug interactions were found in 4 prescriptions.Conclusion The use of tofacitinib tablets in the hospital is fairly reasonable.Problems exist in indications,usage and dosage,and drug interactions.Intervention should be strengthened to ensure the safety of patient medication.
tofacitinib tabletdrug use evaluationrational drug useevaluation criterium
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