Key points in pharmaceutical care of Chinese patent medicines containing toxic animal drugs in China Pharmacopoeia(2020 Edition,Vol.Ⅰ)
Objective To analyze Chinese patent medicines containing toxic animal drugs,and summarize key monitoring points of these medicines.Methods Chinese patent medicines containings toxic animal drugs in China Pharmacopoeia(2020 Edition,Vol.Ⅰ)were summarized,the contents of drug instructions were counted,and the clinical monitoring was sorted out.Results Totally 94 Chinese patent medicines containing toxic animal drugs were included:mainly blood regulating agents,resuscitation agents and tonic formulae according to their functions.Totally 65 animal drugs contained one toxicity,19 contained two toxicity,7 contained three toxicity and 3 contained four toxicity.The contraindications concerning pregnancy,lactation,menstrual period,children,abnormal liver and kidney function in the instructions were specified in most Chinese patent animal drugs containing toxicity.Conclusion To ensure the safety of medication,Chinese patent animal drugs containing toxicity need to be monitored from special population group,patient basic disease,medication courses,drug interactions clarified in the drug instructions,and toxicity accumulation and adverse reactions especially after long time use.
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