Advances in bioanalysis methods and pharmacokinetics of microbubble ultrasound contrast agents
Microbubble ultrasound contrast agent is a kind of drug that can significantly enhance the medical ultrasonic detection signal,and is often used in the ultrasonic examination of the heart,liver,kidney and other parts.Optimizing contrast enhancement imaging and improving diagnostic efficiency require a comprehensive understanding of the pharmacokinetics of microbubble contrast agents in vivo.In this paper,the commonly used biological analysis methods and pharmacokinetic progress of microbubble ultrasound contrast agents were summarized,and the absorption,distribution,metabolism and excretion processes of microbubble ultrasound contrast agents in vivo were systematically explained,hoping to provide references for the research of microbubble drugs.
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