Single-center longitudinal survey of use of narcotic medicine in a hospital
Objective To evaluate the use of narcotic medicine in Nanjing Qixia District Hospital(Qixia Branch of Jiangsu Province Hospital)in the past five years.Methods The clinical data of narcotic medicine were collected from 2019 to 2023,and four main indicators were analyzed:drug utilization indicator,namely cumulative defined daily doses(DDDs);drug price evaluation indicator,defined daily dose cost(DDDc);and B/A value,total drug sales amount(B)to drug utilization DDDs(A),and compound growth rate of operation volume.Results With the deep cooperation between our hospital and Jiangsu Province Hospital,the number of surgeries continued to improve,and the compound annual growth rate reached 22.28％,and the use of narcotic medicine increased accordingly.The DDDs of 2023 reached 6023.39,nearly twice that of 2019(3031.68).A significant difference was found only between 2020 and 2021(P＜0.01).The dosage of oxycodone hydrochloride injection with high DDDc value decreased while remifentanil continued to rank the first place since 2020.The DDDc value of narcotic medicines remained stable,with the maximum value of Oxycodone hydrochloride injection(641.76)and the minimum value of Bucinazine injection(5.76).The B/A of most narcotic medicine maintained around 1,with little change over the five years;the B/A value of Fentanyl injection decreased from 6.00 in 2019 to 2.00 in 2023,while that of Oxycodone hydrochloride injection increased from 0.25 in 2019 to 0.43 in 2023.Conclusion The proportion of narcotic medicine in our hospital is reasonable and can basically meet clinical needs with standardized clinical use.
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