Preparation technology for Wenyang Tongbian granules
Objective To determine and optimize the preparation technology of Wenyang Tongbian granules.Methods Water decoction was extracted.The content of echinacea glycoside in monarch drug and the yield compound were used as indexes.The L9(34)orthogonal test was used to optimize the extraction Wenyang Tongbian granules.The best forming process was optimized based on granulation difficulty,formability and particle yield.Results The optimal extraction included adding 10 folds water and extraction 3 times,1 h each time.The best formation process:the type of auxiliary material was dextrin,the ratio of the ratio of drug to excipient was 1∶0.9,and the best wetting agent was 85％ethanol.Conclusion The extraction and molding process are stable and reasonable,simple and feasible,with good reproducibility,which can provide a basis for the industrial production of Wenyang Tongbian granules.
万方数据
维普
