Rationality of recombinant human erythropoietin injection based on AHM-TOPSIS method
Objective To establish the evaluation criteria for rational application of recombinant human erythropoietin(rhEPO)injection and identify current problems and provide references for its clinical application.Methods Evaluation criteria were developed based on the rhEPO package insert,expert consensus,and guidelines.The criteria were used to evaluate the rationality of rhEPO use in inpatients at the South Branch of Shanghai General Hospital from January to June 2023.Attribute Hierarchy Model(AHM)was used to weight the evaluation indicators,and the Technique for Order Preference by Similarity to an Ideal Solution(TOPSIS)calculated each case's relative closeness(Ci)to the optimal solution.The results were compared with traditional prescription review for consistency and feasibility assessment.Results Among the 572 case reports,111(19.4％)had Ci≥0.8,52(9.1％)had 0.6≤C,＜0.8,while 409(71.5％)had Ci＜0.6.The AHM-TOPSIS method showed 90.6％consistency with the traditional review(Kappa=0.743,P＜0.001).Conclusion The rhEPO evaluation criteria based on AHM-TOPSIS method can be used to evaluate the utilization of rhEPO,indicating common irrational use of rhEPO in the hospital.
recombinant human erythropoietinrationality evaluationAHM-TOPSIS
万方数据
维普
