摘要
目的 研究紫丁香叶的化学成分.方法 运用硅胶、ODS等柱色谱方法及制备型高效液相色谱等技术对紫丁香叶进行系统的提取分离,采用NMR、MS等技术综合解析鉴定化学成分的结构.结果 从紫丁香叶中共分离得到19个化合物,分别鉴定为syringalactone B(1)、(8E)-ligstroside(2)、(8E)-女贞子苷(3)、hydroxyframoside(4)、fraxiformoside(5)、oleoacteoside(6)、丁香苦苷(7)、tetracentronside B(8)、(+)松脂酚-4-O-β-D-吡喃葡萄糖苷(9)、4,4'-dimethoxy-3'-hydroxy-7,9':7',9-diepoxylignan-3-O-β-D-glucopyranoside(10)、lariciresinol-4'-O-β-D-glucopyranoside(11)、olivil-4'-O-β-D-glucopyranoside(12)、isolariciresinol-4-O-β-D-glucopyranoside(13)、紫丁香苷(14)、松柏苷(15)、(4ξ)-α-terpineol 8-O-[α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside](16)、(Z)-3-hexenyl β-D-glucopyranoside(17)、苯甲醇-β-巢菜糖苷(18)、冬绿苷(19).结论 化合物5、10、15、16～19为首次从丁香属植物中分离得到,化合物4、6、12为首次从紫丁香叶中分离得到.
Abstract
Objective To determine the chemical constituents of Syringa oblata(S.oblata)leaves.Methods The chemical components of S.oblata leaves were separated and purified by column chromatography with silica gel,ODS,and preparative HPLC.The structures of the chemical components were determined comprehensively with nuclear magnetic resonance and mass spectrum.Results Totally 19 compounds were isolated ftom S.oblata leaves and identified as syringalactone B(1),(8E)-ligstroside(2),(8E)-ligustroside(3),hydroxyframoside(4),fraxiformoside(5),oleoacteoside(6),syringopicroside(7),tetracentronside B(8),(+)pinoresinol-4-O-β-D-glucopyranoside(9),4,4'-dimethoxy-3'-hydroxy-7,9':7',9-diepoxylignan-3-O-β-D-glucopyranoside(10),lariciresinol-4'-O-β-D-glucopyranoside(11),olivil-4'-O-β-D-glucopyranoside(12),isolariciresinol-4-O-β-D-glucopyranoside(13),syringin(14),coniferin(15),(4ξ)-α-terpineol 8-O-[α-L-arabinopyranosyl-(1 → 6)-β-D-glucopyranoside](16),(Z)-3-hexenyl β-D-glucopyranoside(17),benzyl alcohol-β-vicianoside(18),and gaultherin(19).Conclusion Compounds 5,10,15 and 16～19 have been first isolated from Syringa,and compounds 4,6,12 have been isolated for the first time from S.oblata leaves.
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