Progress in the treatment of acute myeloid leukemia relapse after allogeneic hematopoietic stem cell transplantation
Relapse after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia is a major mortality risk.Currently,there is a lack of consensus regarding the optimal treatment for post-transplant relapse,with common strategies including second allogeneic transplantation,donor lymphocyte infusion,conventional chemotherapy,demethylating agents,targeted therapies,and chimeric antigen receptor T cell therapy.This article comprehensively reviewed the progress in the management of recurrence after allogeneic hematopoietic stem cell transplantation.
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