Research progress in the antidepressant effects and mechanisms of monoterpenoids
Monoterpenoids are important natural product containing two isoprene structures with many pharmacological activities,including anti-inflammation,antioxidation,immune regulation,and neuroprotection,etc.Some monoterpenoids can relieve depressive symptoms by regulating the levels of neurotransmitters,improving the function of the hypothalamic-pituitary-adrenal axis,affecting the levels of neurotrophic factors,and inhibiting the inflammation and oxidative stress,etc.This article summarized natural monoterpenoids with antidepressant effect and summarized their antidepressant mechanism,to provide reference for the treatment and drug development of depression.
monoterpenoidiridoidnatural productantidepressantmechanism of action
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