华中五味子根皮联苯环辛烯型木脂素化学成分研究

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中文摘要：目的研究华中五味子(Schisandra sphenanthera)根皮中联苯环辛烯型木脂素类化学成分.方法运用硅胶色谱法、凝胶色谱法以及半制备高效液相色谱等方法,对华中五味子根皮的石油醚部位进行分离纯化,根据理化性质及波谱数据鉴定分离得到的化合物的结构.结果从华中五味子根皮的石油醚部位分离并鉴定了 15个化合物,分别为当归戈米辛O(1)、schizanrin M(2)、顺芷戈米辛 P(3)、methygomisin O(4)、鹤庆五味子午素(5)、gomosin G(6)、interiotherin B(7)、schizandrin(8)、schisanwilsonin J(9)、schisanwilsonin Ⅰ(10)、schisantherin D(11)、gomisin O(12)、gomisin B(13)、methygomisin R(14)、schisanwilsonin P(15).结论化合物2、5、8～10、15为首次从该植物中分离鉴定.

外文标题：Chemical composition of dibenzocyclooctene lignans from root bark of Schisandra sphenanthera

外文摘要：Objective To determine the chemical constituents of dibenzocyclooctene lignans from the root bark of Schisandra sphenanthera.Methods The petroleum ether parts of Schisandra sphenanthera were separated and purified by silica gel column chromatography,gel column chromatography and semi-preparative high performance liquid chromatography.Their structures were characterized with spectroscopic techniques according to their physicochemical properties.Results Totally 15 compounds were separated from the petroleum ether parts of Schisandra sphenanthera and identified as angeloylgomisin O(1),schizanrin M(2),tigloylgomisin P(3),methygomisin O(4),schisanwilsonin Q(5),gomosin G(6),interiotherin B(7),schizandrin(8),schisanwilsonin J(9),schisanwilsonin Ⅰ(10),schisantherin D(11),gomisin O(12),gomisin B(13),methygomisin R(14),and schisanwilsonin P(15).Conclusion Compounds 2,5,8～10,and 15 have been isolated from Schisandra sphenanthera for the first time.

外文关键词：

Schisandra sphenantheraextraction and separationchemical compositionstructure detectiondibenzocyclooctene lignans

作者：

李昕卓、徐浩南、吴莹、马叶子、李玉泽、邓翀、宋小妹、王薇、张东东

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作者单位：

陕西中医药大学药学院,陕西省太白七药研究与应用重点研究室,陕西咸阳 712046

关键词：

华中五味子提取分离化学成分结构鉴定联苯环辛烯类木脂素

出版年：

2025

DOI：