首页|卷曲乳杆菌对女性生殖道健康的影响及抑菌和抗炎机制

卷曲乳杆菌对女性生殖道健康的影响及抑菌和抗炎机制

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乳杆菌是女性生殖道的重要定植菌,其中的卷曲乳杆菌与生殖道健康密切相关,对维持女性阴道微生态平衡起到重要作用.卷曲乳杆菌丰度降低可能与细菌性阴道病(BV)、外阴阴道假丝酵母菌病(VVC)等多种女性生殖道疾病具有相关性,甚至导致不育、胚胎停育等不良妊娠结局.本文概述了卷曲乳杆菌的基本特性,其数量减少与生殖道疾病的关系,对白假丝酵母菌、衣原体等阴道致病菌的抑制能力及抑菌机制,以及卷曲乳杆菌的抗炎作用,以期为卷曲乳杆菌在阴道用药方面提供参考.
Effect of Lactobacillus crispatus on Female Reproductive Tract Health and Its Antibacterial and Anti-inflammatory Mechanisms
Lactobacilli are important colonizing bacteria in female reproductive tract,among which Lactobacillus cris-patus is closely associated with reproductive tract health and plays a crucial role in maintaining the vaginal microbiota bal-ance.A decrease in the abundance of Lactobacillus crispatus may be correlated with various female reproductive tract dis-eases,such as bacterial vaginosis and vulvovaginal candidiasis,and it can even lead to adverse pregnancy outcomes such as infertility and embryo arrest.This article provides an overview of the basic characteristics of Lactobacillus crispatus,rela-tionship between the decrease of its quantity and reproductive tract diseases,its ability to inhibit pathogenic bacteria such as Candida albicans and Chlamydia trachomatis,and the anti-inflammatory effects of Lactobacillus crispatus.The aim is to provide references for the use of Lactobacillus crispatus in vaginal therapeutics.

LactobacillusLactobacillus crispatusgenital tract healthbacteriostaticanti-inflammatory

孙佳慧、宋丽雅

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北京工商大学化学与材料工程学院,北京 100048

乳杆菌 卷曲乳杆菌 生殖道健康 抑菌 抗炎

北京市科技计划食用菌多糖精深加工技术集成研究及系列产品研制

Z171100001517006

2024

中山大学学报(医学科学版)
中山大学

中山大学学报(医学科学版)

CSTPCD北大核心
影响因子:1.608
ISSN:1672-3554
年,卷(期):2024.45(1)
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