The Significant Roles of Gut-lung Microbiota in Shaping and Regulating Immunity
The interaction between microbes and the human immune system has long been a focus in biomedical re-search.Next-generation sequencing has revealed that in addition to gut microbiota,the respiratory tract also harbors micro-bial communities,forming an interconnected network with the gut microbiota through immune cells and active factors.This review aims to explore how the gut and lung microbiota regulate immune responses,including their roles in local and sys-temic immune modulation.It also delineates the immunological connections along the gut-lung axis.Further elucidating the influence of microbes on the immune system holds important clinical significance for understanding diseases and explor-ing novel diagnostic and therapeutic strategies.
gut microbiotarespiratory microbiotagut-lung axisimmune systemimmune response
万方数据
维普
