Research Progress on NGF and TrkA Receptors in Pediatric Overactive Bladder
Nerve growth factor(NGF)has been widely studied because it plays an important role in the survival,growth and differentiation of nerve cells.It is distributed throughout the body and plays different pathophysiological roles according to the combined receptors.TrkA is its high affinity receptor,and many studies have shown that NGF plays differ-ent roles according to its downstream signal transduction pathways after combining with it.After combining with NGF,it al-so has a cross-effect on other signal transduction pathways that occur in the body.This paper reviews the signal transduc-tion pathways combined with NGF and TrkA from different disease symptoms,so as to explore the role of NGF/TrkA signal pathways in children with overactive bladder.
国家科技期刊平台
NSTL
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