首页|硬膜外电刺激促进脊髓损伤后运动障碍恢复的研究进展

硬膜外电刺激促进脊髓损伤后运动障碍恢复的研究进展

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近年来,脊髓损伤(SCI)的发病率呈现日益增长的趋势,由此引发的运动障碍给患者本身及社会带来沉重的负担.尽管目前临床上对SCI后运动障碍的治疗手段多样,主要集中在通过给予外在刺激的方法改善功能障碍,提高患者日常生活能力,但仍缺乏根治性的方案.硬膜外电刺激(EES)作为一种新兴的治疗技术,已在多项国际临床研究中显示出对SCI后运动功能恢复的显著潜力,具有疗效显著、方便易行、适用广泛、可调节性强等优势,对SCI后运动障碍的康复有很多大助益,在脊髓损伤康复中有很大的发展前景.然而目前国内的大多数研究多局限于SCI后自主神经功能异常导致的神经源性膀胱等,且多为中西医结合康复治疗,对EES这一新兴疗法少有集中研究,本文旨在综述EES的基本原理、潜在作用机制以及其在SCI后运动障碍治疗中的临床应用进展,以期为EES治疗SCI后运动障碍的临床应用和科学研究提供参考.
Research Progress on Epidural Electrical Stimulation for Motor Disorders after Spinal Cord Injury
In recent years,the incidence of spinal cord injury(SCI)has shown an increasing trend,and the resulting motor impairment cause significant harm to patients themselves and public health.Although the current clinical treatments for motor disorders after SCI are diverse,mainly focusing on improving dysfunction and improving patients' daily living ability through external stimulation,there is still a lack of radical solutions.Epidural electrical stimulation(EES)as an emerging treatment technology,has been shown in a number of international clinical studies on the SCI significant poten-tial of motor function recovery,has significant curative effect,convenient,widely applicable,adjustable advantages,the rehabilitation of movement disorders after SCI has a lot of big benefits,in the spinal cord injury rehabilitation has great prospect.However,most of the domestic research are limited to the neurogenic bladder caused by abnormal autonomic nerve function after SCI,and mostly combine traditional Chinese and western medicine rehabilitation treatment,the emerging therapy of EES,this paper aims to review the basic principle of EES,potential mechanism of action and its c lini-cal application progress in the treatment of movement disorders after SCI,in order to provide reference for the clinical ap-plication and scientific research of EES treatment of motor disorders after SCI.

spinal cord injury(SCI)epidural electrical stimulation(EES)motor impairmentrehabilitationreview

吴新、任彬彬

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河南中医药大学康复医学院,河南中医药大学第一附属医院,河南 郑州 450000

河南中医药大学第一附属医院康复中心,河南 郑州 450000

脊髓损伤 硬膜外电刺激 运动障碍 康复 综述

中医药传承与创新人才工程(仲景工程)2022年度河南省中医药拔尖人才培养项目专项课题

2022ZYBJ09

2024

中山大学学报(医学科学版)
中山大学

中山大学学报(医学科学版)

CSTPCD北大核心
影响因子:1.608
ISSN:1672-3554
年,卷(期):2024.45(4)