Curriculum reform and practice of computer-aided drug design in Chinese medicine colleges and universities
Computer-aided drug design(CADD)is based on mathematics,medicinal chemistry,biochemistry,molecular biology,structural chemistry and other disciplines,quantum chemistry,molecular mechanics and other theoretical basis,with the help of computers for rational drug design.It is not only an interdisciplinary theoretical discipline,but also has a strong practical.Computer-aided drug design technology has its unique advantages in the screening of Chinese medicine active ingredients,target discovery,toxicity prediction and prescription mechanism research.Interdisciplinary research is the trend of the rapid development of science and technology and medicine.Under the guidance of traditional Chinese medicine theory,the study of pharmacology,methods,prescriptions and drugs of traditional Chinese medicine by means of computer-aided drug design combined with modern biological methods can greatly promote the breadth and depth of traditional Chinese medicine research.Students in Chinese medicine colleges can learn the theory and practical knowledge of computer-aided drug design,which can prepare for future interdisciplinary drug research and development.Therefore,the development of computer-aided drug design and other cross-attribute courses in Chinese medicine colleges and universities is conducive to the cultivation of interdisciplinary talents in Chinese medicine,and the establishment of computer-aided drug design teaching mode suitable for students in Chinese medicine colleges and universities will play a great role in exploring the essence of the treasure house of Chinese medicine and accelerating the modernization of Chinese medicine.Based on these,this paper combined with the author's teaching experience and the characteristics of the development of the times,in the course of computer-aided drug design course to introduce teaching concepts such as paying attention to the foundation,focusing on the Chinese and western,emphasizing on practice,in the process of training multi-disciplinary interdisciplinary talents in the process of achieving obvious results.Through the teaching reform and practice of computer-aided drug design in Chinese medicine major,this paper discusses and summarizes the teaching effect of this course in a deep and all-round way,and lays a foundation for training compound Chinese medicine talents and expanding the employment of Chinese medicine college students.
computer-aided drug designtraditional Chinese medicine colleges and universitiescross-innovationteaching reform
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