The effect of quinestrol on reproductive system of male Yangtze vole, Microtus fortis
In order to explore the effect of quinestrol and progestin ( EP-1 ) on reproductive system, ap- propriate concentration and reproduction recover duration of male Yangtze voles, Microtus fortis, the ex- perimental voles were treated using gastric perfusion with EP-1 and some of them were dissected at differ- ent time. The results showed that EP-1 affected the anti-fertility of male Yangtze vole and the effect could recover. Compared to the control group, testicular coefficient and epididymis coefficient were decreased significantly (P 〈 O. 01 ) , testicle atrophied and be damaged, sperm density and testosterone contents de- creased, lower rate of reproduction as well. The effective fertility control time of group were about 40, 55 and 60 d for 10, 30, 60 mg/kg respectively. The recover order of reproductive tissue was testicle, epidid- ymis, and sperm.
male Microtusfortisreproduction recoverEP-1anti-fertility