Current status,mechanism,and management strategy of codling moth Cydia pomonella resistance to lambda-cyhalothrin
The codling moth,Cydia pomonella,is a major invasive pest of pome fruits,found on six continents and causing serious damage to global fruit production.Currently,the management of C.po-monella mainly relies on the application of insecticides,which has led to the development of insecticide resistance.Two major types of insecticide resistance mechanisms-metabolic resistance and target resistance-have been documented in this species.The most common resistance mechanism involves the overexpression of detoxification enzyme genes encoding cytochrome P450 monooxygenases(P450s),carboxylesterases(CarEs),and glutathione S-transferases(GSTs),which enhances the metabolic capac-ity of C.pomonella to break down insecticides.Given the prominent problem of C.pomonella's resis-tance to lambda-cyhalothrin and the need to maximize the effectiveness of this insecticidefor control-ling the pest,it is essential to develop reasonable resistance management strategies based on comprehen-sive understanding the resistance mechanisms.This review summarized the current status of C.po-monella resistance to lambda-cyhalothrin,explores the underlying resistance mechanisms,and dis-cusses strategies for effective insecticide resistance management in C.pomonella.